Don't know a way to permanently disable it, but phantom power isn't easy to ACCIDENTALLY turn on. And in the input trim panel, you can see the status of ALL input channels phantom power immediately IN RED if on and White if OFF. The mixer defaults to staying is the last mode after shut down. So unless you have shows saved with phantom power on, you aren't likely to be turning it on without a reason to. (And it's not global on this mixer. You have to turn it on by the channel.)